Detection of promoter methylation of tumor suppressor genes in serum DNA of breast cancer cases and benign breast disease controls

Tumors are capable of shedding DNA into the blood stream. This shed DNA may be recovered from serum or plasma. The objective of this study was to evaluate whether pyrosequencing promoter DNA in a panel of 12 breast cancer-related genes (APC, BRCA1, CCND2, CDH1, ESR1, GSTP1, HIN1, P16, RARβ, RASSF1,...

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Main Authors: Sturgeon, Susan R., Balasubramanian, Raji, Schairer, Catherine, Muss, Hyman B., Ziegler, Regina G., Arcaro, Kathleen F.
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2012
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499327/
https://ncbi.nlm.nih.gov/pubmed/22986510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.22220
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