Detection of promoter methylation of tumor suppressor genes in serum DNA of breast cancer cases and benign breast disease controls

Tumors are capable of shedding DNA into the blood stream. This shed DNA may be recovered from serum or plasma. The objective of this study was to evaluate whether pyrosequencing promoter DNA in a panel of 12 breast cancer-related genes (APC, BRCA1, CCND2, CDH1, ESR1, GSTP1, HIN1, P16, RARβ, RASSF1,...

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Bibliografische gegevens
Hoofdauteurs: Sturgeon, Susan R., Balasubramanian, Raji, Schairer, Catherine, Muss, Hyman B., Ziegler, Regina G., Arcaro, Kathleen F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2012
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499327/
https://ncbi.nlm.nih.gov/pubmed/22986510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.22220
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