Detection of promoter methylation of tumor suppressor genes in serum DNA of breast cancer cases and benign breast disease controls

Tumors are capable of shedding DNA into the blood stream. This shed DNA may be recovered from serum or plasma. The objective of this study was to evaluate whether pyrosequencing promoter DNA in a panel of 12 breast cancer-related genes (APC, BRCA1, CCND2, CDH1, ESR1, GSTP1, HIN1, P16, RARβ, RASSF1,...

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Hlavní autoři: Sturgeon, Susan R., Balasubramanian, Raji, Schairer, Catherine, Muss, Hyman B., Ziegler, Regina G., Arcaro, Kathleen F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499327/
https://ncbi.nlm.nih.gov/pubmed/22986510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.22220
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