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Transmembrane domains are critical to the interaction between platelet glycoprotein V and glycoprotein Ib-IX complex

BACKGROUND: The glycoprotein (GP) Ib-IX-V complex, the von Willebrand factor receptor on platelet surface, is critically involved in hemostasis and thrombosis. GPV subunit interacts with GPIb-IX to form the GPIb-IX-V complex, but the underlying molecular basis remains unclear. It was observed earlie...

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Main Authors: Mo, Xi, Liu, Lanbo, López, José A., Li, Renhao
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499136/
https://ncbi.nlm.nih.gov/pubmed/22759073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2012.04841.x
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