CRTH2 Is A Critical Regulator of Neutrophil Migration and Resistance to Polymicrobial Sepsis

Although arachidonic acid cascade has been shown to be involved in sepsis, little is known about the role of prostaglandin D(2) and its newly found receptor, chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2), on the septic response. Severe sepsis is associated with the fail...

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Hlavní autoři: Ishii, Makoto, Asano, Koichiro, Namkoong, Ho, Tasaka, Sadatomo, Mizoguchi, Kosuke, Asami, Takahiro, Kamata, Hirofumi, Kimizuka, Yoshifumi, Fujiwara, Hiroshi, Funatsu, Yohei, Kagawa, Shizuko, Miyata, Jun, Ishii, Ken, Nakamura, Masataka, Hirai, Hiroyuki, Nagata, Kinya, Kunkel, Steven L., Hasegawa, Naoki, Betsuyaku, Tomoko
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498953/
https://ncbi.nlm.nih.gov/pubmed/22544936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102330
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