Targeting C/EBP homologous protein with siRNA attenuates cerebral vasospasm after experimental subarachnoid hemorrhage

Endothelial apoptosis plays a major role in the development of cerebral vascular spasm after subarachnoid hemorrhage (SAH). C/EBP homologous protein (CHOP) orchestrates apoptosis in a variety of cell types in response to endoplasmic reticulum (ER) stress, implicated in the brain injury after SAH. Ho...

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Autori principali: He, Zhaohui, Ostrowski, Robert P., Sun, Xiaochuan, Ma, Qingyi, Tang, Jiping, Zhang, John H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498605/
https://ncbi.nlm.nih.gov/pubmed/22944263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.08.025
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