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ADH and ALDH polymorphisms and alcohol dependence in Mexican and Native Americans

BACKGROUND: Ethanol is primarily metabolized in the liver by 2 rate-limiting reactions: conversion of ethanol to acetaldehyde by alcohol dehydrogenase (ADH) and subsequent conversion of acetaldehyde to acetate by aldehyde dehydrogenase (ALDH). ADH and ALDH exist in multiple isozymes that differ in t...

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Detaylı Bibliyografya
Asıl Yazarlar: Ehlers, Cindy L., Liang, Tiebing, Gizer, Ian R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498484/
https://ncbi.nlm.nih.gov/pubmed/22931071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00952990.2012.694526
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