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ADH and ALDH polymorphisms and alcohol dependence in Mexican and Native Americans

BACKGROUND: Ethanol is primarily metabolized in the liver by 2 rate-limiting reactions: conversion of ethanol to acetaldehyde by alcohol dehydrogenase (ADH) and subsequent conversion of acetaldehyde to acetate by aldehyde dehydrogenase (ALDH). ADH and ALDH exist in multiple isozymes that differ in t...

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Detalhes bibliográficos
Main Authors: Ehlers, Cindy L., Liang, Tiebing, Gizer, Ian R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498484/
https://ncbi.nlm.nih.gov/pubmed/22931071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00952990.2012.694526
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