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ADH and ALDH polymorphisms and alcohol dependence in Mexican and Native Americans
BACKGROUND: Ethanol is primarily metabolized in the liver by 2 rate-limiting reactions: conversion of ethanol to acetaldehyde by alcohol dehydrogenase (ADH) and subsequent conversion of acetaldehyde to acetate by aldehyde dehydrogenase (ALDH). ADH and ALDH exist in multiple isozymes that differ in t...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3498484/ https://ncbi.nlm.nih.gov/pubmed/22931071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00952990.2012.694526 |
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