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Changes in Response Properties of RVM Neurons during Prolonged Inflammation: Modulation by NK-1 Receptors

Activation of neurokinin-1 (NK-1) receptors in the rostral ventromedial medulla (RVM) can facilitate pain transmission in conditions such as inflammation, and thereby contribute to hyperalgesia. Since blockade of NK-1 receptors in the RVM can attenuate hyperalgesia produced by prolonged inflammation...

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Main Authors: Khasabov, Sergey G., Brink, Thaddeus, Schupp, Marianna, Noack, Joseph, Simone, Donald A.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498481/
https://ncbi.nlm.nih.gov/pubmed/22917610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.08.029
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