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Hyperalgesia and sensitization of dorsal horn neurons following activation of NK-1 receptors in the rostral ventromedial medulla

Neurons in the rostral ventromedial medulla (RVM) project to the spinal cord and are involved in descending modulation of pain. Several studies have shown that activation of neurokinin-1 (NK-1) receptors in the RVM produces hyperalgesia, although the underlying mechanisms are not clear. In parallel...

詳細記述

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書誌詳細
出版年:J Neurophysiol
主要な著者: Khasabov, Sergey G., Malecha, Patrick, Noack, Joseph, Tabakov, Janneta, Giesler, Glenn J., Simone, Donald A.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675905/
https://ncbi.nlm.nih.gov/pubmed/28794197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00478.2017
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