Hyperalgesia and sensitization of dorsal horn neurons following activation of NK-1 receptors in the rostral ventromedial medulla

Neurons in the rostral ventromedial medulla (RVM) project to the spinal cord and are involved in descending modulation of pain. Several studies have shown that activation of neurokinin-1 (NK-1) receptors in the RVM produces hyperalgesia, although the underlying mechanisms are not clear. In parallel...

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Bibliografski detalji
Izdano u:J Neurophysiol
Glavni autori: Khasabov, Sergey G., Malecha, Patrick, Noack, Joseph, Tabakov, Janneta, Giesler, Glenn J., Simone, Donald A.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675905/
https://ncbi.nlm.nih.gov/pubmed/28794197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00478.2017
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