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Inhibition of HIV-1 particle assembly by 2',3'-cyclic-nucleotide 3'-phosphodiesterase

The expression of hundreds of interferon-stimulated genes (ISGs) causes the cellular ‘antiviral state’ in which the replication of many viruses, including HIV-1, is attenuated. We conducted a screen for ISGs that inhibit HIV-1 virion production and found that 2',3'-cyclic-nucleotide 3'...

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Detalhes bibliográficos
Main Authors: Wilson, Sam J., Schoggins, John W., Zang, Trinity, Kutluay, Sebla B., Jouvenet, Nolwenn, Alim, Mudathir A., Bitzegeio, Julia, Rice, Charles M., Bieniasz, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498451/
https://ncbi.nlm.nih.gov/pubmed/23084924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.08.012
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