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Diastereomeric specificity of 2',3'-cyclic nucleotide 3'-phosphodiesterase.

The diastereomers of adenosine and uridine 2',3'-cyclic phosphorothioates were tested as substrates for 2',3'-cyclic nucleotide 3'-phosphodiesterase from bovine brain. The enzyme cleaves the Sp (or exo) diastereomers efficiently, whereas the Rp (or endo) diastereomers are re...

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Библиографические подробности
Главные авторы: Heaton, P A, Eckstein, F
Формат: Artigo
Язык:Inglês
Опубликовано: 1996
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC145708/
https://ncbi.nlm.nih.gov/pubmed/8600451
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