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Isolated Toll-like Receptor Transmembrane Domains Are Capable of Oligomerization
Toll-like receptors (TLRs) act as the first line of defense against bacterial and viral pathogens by initiating critical defense signals upon dimer activation. The contribution of the transmembrane domain in the dimerization and signaling process has heretofore been overlooked in favor of the extrac...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3498381/ https://ncbi.nlm.nih.gov/pubmed/23155421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048875 |
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