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Probabilistic Prediction of Contacts in Protein-Ligand Complexes

We introduce a statistical method for evaluating atomic level 3D interaction patterns of protein-ligand contacts. Such patterns can be used for fast separation of likely ligand and ligand binding site combinations out of all those that are geometrically possible. The practical purpose of this probab...

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Bibliographic Details
Main Authors: Hakulinen, Riku, Puranen, Santeri, Lehtonen, Jukka V., Johnson, Mark S., Corander, Jukka
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498326/
https://ncbi.nlm.nih.gov/pubmed/23155467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049216
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