A Truncated AdeS Kinase Protein Generated by ISAba1 Insertion Correlates with Tigecycline Resistance in Acinetobacter baumannii

Over-expression of AdeABC efflux pump stimulated continuously by the mutated AdeRS two component system has been found to result in antimicrobial resistance, even tigecycline (TGC) resistance, in multidrug-resistant Acinetobacter baumannii (MRAB). Although the insertion sequence, ISAba1, contributes...

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Bibliografiske detaljer
Main Authors: Sun, Jun-Ren, Perng, Cherng-Lih, Chan, Ming-Chin, Morita, Yuji, Lin, Jung-Chung, Su, Chih-Mao, Wang, Wei-Yao, Chang, Tein-Yao, Chiueh, Tzong-Shi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498117/
https://ncbi.nlm.nih.gov/pubmed/23166700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049534
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