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Advantages and limitations of cell-based assays for GTPase activation and regulation

Small GTPases of the Ras superfamily are important regulators of many cellular functions, including signal transduction, cytoskeleton assembly, metabolic regulation, organelle biogenesis and intracellular transport. Most GTPases act as binary switches, being “on” in the active, GTP-bound state and “...

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Bibliografski detalji
Glavni autor: Casanova, James E.
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498073/
https://ncbi.nlm.nih.gov/pubmed/23181197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cl.22045
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