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Advantages and limitations of cell-based assays for GTPase activation and regulation

Small GTPases of the Ras superfamily are important regulators of many cellular functions, including signal transduction, cytoskeleton assembly, metabolic regulation, organelle biogenesis and intracellular transport. Most GTPases act as binary switches, being “on” in the active, GTP-bound state and “...

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Hlavní autor: Casanova, James E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498073/
https://ncbi.nlm.nih.gov/pubmed/23181197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cl.22045
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