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Advantages and limitations of cell-based assays for GTPase activation and regulation
Small GTPases of the Ras superfamily are important regulators of many cellular functions, including signal transduction, cytoskeleton assembly, metabolic regulation, organelle biogenesis and intracellular transport. Most GTPases act as binary switches, being “on” in the active, GTP-bound state and “...
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| Hovedforfatter: | |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3498073/ https://ncbi.nlm.nih.gov/pubmed/23181197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cl.22045 |
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