Persister-promoting bacterial toxin TisB produces anion-selective pores in planar lipid bilayers

We studied membrane activity of the bacterial peptide TisB involved in persister cell formation. TisB and its analogs form multi-state ion-conductive pores in planar lipid bilayers with all states of pores displaying similar anionic selectivity. TisB analogs differing by ±1 elementary charges show c...

Full description

Saved in:
Bibliographic Details
Main Authors: Gurnev, Philip A., Ortenberg, Ron, Dörr, Tobias, Lewis, Kim, Bezrukov, Sergey M.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498054/
https://ncbi.nlm.nih.gov/pubmed/22728134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.06.021
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items