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Use of a repetitive seeding protocol to obtain diffraction-quality crystals of a putative human d-xylulokinase

In mammals, the enzyme d-xylulokinase (XK; EC 2.7.1.17) catalyses the last step of the glucuronate–xylulose pathway, in which the ketopentose sugar d-xylulose is phosphorylated to yield d-xylulose 5-phosphate (Xu5P). Xu5P is also a metabolite of the pentose phosphate pathway and acts as a signalling...

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Detalhes bibliográficos
Main Authors: Bunker, Richard D., Dickson, James M. J., Caradoc-Davies, Tom T., Loomes, Kerry M., Baker, Edward N.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497992/
https://ncbi.nlm.nih.gov/pubmed/23027762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112031181
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