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Extensive genetic variation in somatic human tissues

Genetic variation between individuals has been extensively investigated, but differences between tissues within individuals are far less understood. It is commonly assumed that all healthy cells that arise from the same zygote possess the same genomic content, with a few known exceptions in the immu...

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Autori principali: O’Huallachain, Maeve, Karczewski, Konrad J., Weissman, Sherman M., Urban, Alexander Eckehart, Snyder, Michael P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497787/
https://ncbi.nlm.nih.gov/pubmed/23043118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213736109
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