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Effects of dopamine depletion on LFP oscillations in striatum are task- and learning-dependent and selectively reversed by l-DOPA

A major physiologic sign in Parkinson disease is the occurrence of abnormal oscillations in cortico-basal ganglia circuits, which can be normalized by l-DOPA therapy. Under normal circumstances, oscillatory activity in these circuits is modulated as behaviors are learned and performed, but how dopam...

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Detalhes bibliográficos
Main Authors: Lemaire, Nuné, Hernandez, Ledia F., Hu, Dan, Kubota, Yasuo, Howe, Mark W., Graybiel, Ann M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497773/
https://ncbi.nlm.nih.gov/pubmed/23074253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216403109
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