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Distinct mode of methylated lysine-4 of histone H3 recognition by tandem tudor-like domains of Spindlin1

Recognition of methylated histone tail lysine residues by tudor domains plays important roles in epigenetic control of gene expression and DNA damage response. Previous studies revealed the binding of methyllysine in a cage of aromatic residues, but the molecular mechanism by which the sequence spec...

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Autores principales: Yang, Na, Wang, Weixiang, Wang, Yan, Wang, Mingzhu, Zhao, Qiang, Rao, Zihe, Zhu, Bing, Xu, Rui-Ming
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497761/
https://ncbi.nlm.nih.gov/pubmed/23077255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208517109
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