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Distinct mode of methylated lysine-4 of histone H3 recognition by tandem tudor-like domains of Spindlin1

Recognition of methylated histone tail lysine residues by tudor domains plays important roles in epigenetic control of gene expression and DNA damage response. Previous studies revealed the binding of methyllysine in a cage of aromatic residues, but the molecular mechanism by which the sequence spec...

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Detalhes bibliográficos
Main Authors: Yang, Na, Wang, Weixiang, Wang, Yan, Wang, Mingzhu, Zhao, Qiang, Rao, Zihe, Zhu, Bing, Xu, Rui-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497761/
https://ncbi.nlm.nih.gov/pubmed/23077255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208517109
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