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N-terminal domain of vacuolar SNARE Vam7p promotes trans-SNARE complex assembly

SNARE-dependent membrane fusion in eukaryotic cells requires that the heptad-repeat SNARE domains from R- and Q-SNAREs, anchored to apposed membranes, assemble into four-helix coiled-coil bundles. In addition to their SNARE and transmembrane domains, most SNAREs have N-terminal domains (N-domains),...

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Autors principals: Xu, Hao, Wickner, William T.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497749/
https://ncbi.nlm.nih.gov/pubmed/23071309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216201109
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