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Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II
The X-ray crystal structure of the Head module, one-third of the Mediator of transcriptional regulation, has been determined as a complex with the C-terminal domain (CTD) of RNA polymerase II. The structure reveals multiple points of interaction with an extended conformation of the CTD; it suggests...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497735/ https://ncbi.nlm.nih.gov/pubmed/23071300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215241109 |
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