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BRCA1 Can Modulate RNA Polymerase II Carboxy-Terminal Domain Phosphorylation Levels

A high incidence of breast and ovarian cancers has been linked to mutations in the BRCA1 gene. BRCA1 has been shown to be involved in both positive and negative regulation of gene activity as well as in numerous other processes such as DNA repair and cell cycle regulation. Since modulation of the RN...

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Détails bibliographiques
Auteurs principaux: Moisan, Annie, Larochelle, Chantal, Guillemette, Benoît, Gaudreau, Luc
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC479726/
https://ncbi.nlm.nih.gov/pubmed/15282296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.16.6947-6956.2004
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