BRCA1 Can Modulate RNA Polymerase II Carboxy-Terminal Domain Phosphorylation Levels

A high incidence of breast and ovarian cancers has been linked to mutations in the BRCA1 gene. BRCA1 has been shown to be involved in both positive and negative regulation of gene activity as well as in numerous other processes such as DNA repair and cell cycle regulation. Since modulation of the RN...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Moisan, Annie, Larochelle, Chantal, Guillemette, Benoît, Gaudreau, Luc
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2004
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC479726/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15282296/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.16.6947-6956.2004
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