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BRCA1 Can Modulate RNA Polymerase II Carboxy-Terminal Domain Phosphorylation Levels

A high incidence of breast and ovarian cancers has been linked to mutations in the BRCA1 gene. BRCA1 has been shown to be involved in both positive and negative regulation of gene activity as well as in numerous other processes such as DNA repair and cell cycle regulation. Since modulation of the RN...

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Detalhes bibliográficos
Main Authors: Moisan, Annie, Larochelle, Chantal, Guillemette, Benoît, Gaudreau, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC479726/
https://ncbi.nlm.nih.gov/pubmed/15282296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.16.6947-6956.2004
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