Amino Acid Residue-Specific Neutralization and Nonneutralization of Hepatitis C Virus by Monoclonal Antibodies to the E2 Protein

Antibodies to epitopes in the E2 protein of hepatitis C virus (HCV) reduce the viral infectivity in vivo and in vitro. However, the virus can persist in patients in the presence of neutralizing antibodies. In this study, we generated a panel of monoclonal antibodies that bound specifically to the re...

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Detalhes bibliográficos
Main Authors: Duan, Hongying, Kachko, Alla, Zhong, Lilin, Struble, Evi, Pandey, Shivani, Yan, Hailing, Harman, Christine, Virata-Theimer, Maria Luisa, Deng, Lu, Zhao, Zhong, Major, Marian, Feinstone, Stephen, Zhang, Pei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497666/
https://ncbi.nlm.nih.gov/pubmed/22973024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00994-12
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