Human Metapneumovirus M2-2 Protein Inhibits Innate Cellular Signaling by Targeting MAVS

Human metapneumovirus (hMPV) is a leading cause of respiratory infections in pediatric populations globally, with no prophylactic or therapeutic measures. Recently, a recombinant hMPV lacking the M2-2 protein (rhMPV-ΔM2-2) demonstrated reduced replication in the respiratory tract of animal models, m...

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Detalhes bibliográficos
Main Authors: Ren, Junping, Wang, Qingrong, Kolli, Deepthi, Prusak, Deborah J., Tseng, Chien-Te K., Chen, Zhijian J., Li, Kui, Wood, Thomas G., Bao, Xiaoyong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497653/
https://ncbi.nlm.nih.gov/pubmed/23015697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01248-12
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