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Characterization of Conserved Region 2-Deficient Mutants of the Cytomegalovirus Egress Protein pM53
Dominant-negative (DN) mutants are powerful tools for studying essential protein-protein interactions. A systematic genetic screen of the essential murine cytomegalovirus (MCMV) protein pM53 identified the accumulation of inhibitory mutations within conserved region 2 (CR2) and CR4. The strong inhib...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497646/ https://ncbi.nlm.nih.gov/pubmed/22993161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00471-12 |
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