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A Modified Screening System for Loss-of-Function and Dominant Negative Alleles of Essential MCMV Genes
Inactivation of gene products by dominant negative mutants is a valuable tool to assign functions to yet uncharacterized proteins, to map protein-protein interactions or to dissect physiological pathways. Detailed functional and structural knowledge about the target protein would allow the construct...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3986410/ https://ncbi.nlm.nih.gov/pubmed/24733555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094918 |
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