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A Modified Screening System for Loss-of-Function and Dominant Negative Alleles of Essential MCMV Genes

Inactivation of gene products by dominant negative mutants is a valuable tool to assign functions to yet uncharacterized proteins, to map protein-protein interactions or to dissect physiological pathways. Detailed functional and structural knowledge about the target protein would allow the construct...

詳細記述

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書誌詳細
主要な著者: Pogoda, Madlen, Bosse, Jens B., Conzelmann, Karl-Klaus, Koszinowski, Ulrich H., Ruzsics, Zsolt
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986410/
https://ncbi.nlm.nih.gov/pubmed/24733555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094918
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