EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer

BACKGROUND: Cancer stem cells are thought to be responsible for the initiation and progression of cancers. In non-small cell lung cancers (NSCLCs), Hoechst 33342 dye effluxing side population (SP) cells are shown to have stem cell like properties. The oncogenic capacity of cancer stem-like cells is...

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Bibliographische Detailangaben
Hauptverfasser: Singh, Sandeep, Trevino, Jose, Bora-Singhal, Namrata, Coppola, Domenico, Haura, Eric, Altiok, Soner, Chellappan, Srikumar P
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497614/
https://ncbi.nlm.nih.gov/pubmed/23009336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-73
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