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FMS-Like Tyrosine Kinase 3 Ligand Treatment of Mice Aggravates Acute Lung Injury in Response to Streptococcus pneumoniae: Role of Pneumolysin

FMS-like tyrosine kinase-3 ligand (Flt3L) is a dendritic cell (DC) growth and differentiation factor with potential in antitumor therapies and antibacterial immunization strategies. However, the effect of systemic Flt3L treatment on lung-protective immunity against bacterial infection is incompletel...

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Detalhes bibliográficos
Main Authors: Brumshagen, Christina, Maus, Regina, Bischof, Andrea, Ueberberg, Bianca, Bohling, Jennifer, Osterholzer, John J., Ogunniyi, Abiodun D., Paton, James C., Welte, Tobias, Maus, Ulrich A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497444/
https://ncbi.nlm.nih.gov/pubmed/23006850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00854-12
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