TNF-related apoptosis-inducing ligand (TRAIL) exerts therapeutic efficacy for the treatment of pneumococcal pneumonia in mice

Apoptotic death of alveolar macrophages observed during lung infection with Streptococcus pneumoniae is thought to limit overwhelming lung inflammation in response to bacterial challenge. However, the underlying apoptotic death mechanism has not been defined. Here, we examined the role of the TNF su...

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Main Authors: Steinwede, Kathrin, Henken, Stefanie, Bohling, Jennifer, Maus, Regina, Ueberberg, Bianca, Brumshagen, Christina, Brincks, Erik L., Griffith, Thomas S., Welte, Tobias, Maus, Ulrich A.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478925/
https://ncbi.nlm.nih.gov/pubmed/23071253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120983
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