Susceptibility to Progressive Cryptococcus neoformans Pulmonary Infection Is Regulated by Loci on Mouse Chromosomes 1 and 9

Genetic factors that regulate the pathogenesis of pneumonia caused by the fungus Cryptococcus neoformans are poorly understood. Through a phenotypic strain survey we observed that inbred C3H/HeN mice develop a significantly greater lung fungal burden than mice of the resistant CBA/J strain 4 weeks f...

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Bibliographic Details
Main Authors: Carroll, Scott F., Lafferty, Erin I., Flaczyk, Adam, Fujiwara, T. Mary, Homer, Robert, Morgan, Kenneth, Loredo-Osti, J C., Qureshi, Salman T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497416/
https://ncbi.nlm.nih.gov/pubmed/22988020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00417-12
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