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The Cnes2 Locus on Mouse Chromosome 17 Regulates Host Defense against Cryptococcal Infection through Pleiotropic Effects on Host Immunity

The genetic basis of natural susceptibility to progressive Cryptococcus neoformans infection is not well understood. Using C57BL/6 and CBA/J inbred mice, we previously identified three chromosomal regions associated with C. neoformans susceptibility (Cnes1, Cnes2, and Cnes3). To validate and charact...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Shourian, Mitra, Flaczyk, Adam, Angers, Isabelle, Mindt, Barbara C., Fritz, Jörg H., Qureshi, Salman T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645399/
https://ncbi.nlm.nih.gov/pubmed/26371125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00697-15
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