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The Cnes2 Locus on Mouse Chromosome 17 Regulates Host Defense against Cryptococcal Infection through Pleiotropic Effects on Host Immunity

The genetic basis of natural susceptibility to progressive Cryptococcus neoformans infection is not well understood. Using C57BL/6 and CBA/J inbred mice, we previously identified three chromosomal regions associated with C. neoformans susceptibility (Cnes1, Cnes2, and Cnes3). To validate and charact...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Shourian, Mitra, Flaczyk, Adam, Angers, Isabelle, Mindt, Barbara C., Fritz, Jörg H., Qureshi, Salman T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645399/
https://ncbi.nlm.nih.gov/pubmed/26371125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00697-15
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