The Cnes2 Locus on Mouse Chromosome 17 Regulates Host Defense against Cryptococcal Infection through Pleiotropic Effects on Host Immunity

The genetic basis of natural susceptibility to progressive Cryptococcus neoformans infection is not well understood. Using C57BL/6 and CBA/J inbred mice, we previously identified three chromosomal regions associated with C. neoformans susceptibility (Cnes1, Cnes2, and Cnes3). To validate and charact...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Shourian, Mitra, Flaczyk, Adam, Angers, Isabelle, Mindt, Barbara C., Fritz, Jörg H., Qureshi, Salman T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645399/
https://ncbi.nlm.nih.gov/pubmed/26371125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00697-15
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