Crucial Role of Gamma Interferon-Producing CD4(+) Th1 Cells but Dispensable Function of CD8(+) T Cell, B Cell, Th2, and Th17 Responses in the Control of Brucella melitensis Infection in Mice

Brucella spp. are facultative intracellular bacterial pathogens responsible for brucellosis, a worldwide zoonosis that causes abortion in domestic animals and chronic febrile disease associated with serious complications in humans. There is currently no approved vaccine against human brucellosis, an...

Full description

Saved in:
Bibliographic Details
Main Authors: Vitry, Marie-Alice, De Trez, Carl, Goriely, Stanislas, Dumoutier, Laure, Akira, Shizuo, Ryffel, Bernhard, Carlier, Yves, Letesson, Jean-Jacques, Muraille, Eric
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Bacterial Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497404/
https://ncbi.nlm.nih.gov/pubmed/23006848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00761-12
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items