Crucial Role of Gamma Interferon-Producing CD4(+) Th1 Cells but Dispensable Function of CD8(+) T Cell, B Cell, Th2, and Th17 Responses in the Control of Brucella melitensis Infection in Mice

Brucella spp. are facultative intracellular bacterial pathogens responsible for brucellosis, a worldwide zoonosis that causes abortion in domestic animals and chronic febrile disease associated with serious complications in humans. There is currently no approved vaccine against human brucellosis, an...

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Detalhes bibliográficos
Main Authors: Vitry, Marie-Alice, De Trez, Carl, Goriely, Stanislas, Dumoutier, Laure, Akira, Shizuo, Ryffel, Bernhard, Carlier, Yves, Letesson, Jean-Jacques, Muraille, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497404/
https://ncbi.nlm.nih.gov/pubmed/23006848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00761-12
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