Insulin Treatment Directly Restores Neutrophil Phagocytosis and Bactericidal Activity in Diabetic Mice and Thereby Improves Surgical Site Staphylococcus aureus Infection

Bacterial infections, including surgical site infections (SSI), are a common and serious complication of diabetes. Staphylococcus aureus, which is eliminated mainly by neutrophils, is a major cause of SSI in diabetic patients. However, the precise mechanisms by which diabetes predisposes to staphylo...

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Main Authors: Yano, Hidekazu, Kinoshita, Manabu, Fujino, Keiichi, Nakashima, Masahiro, Yamamoto, Yoritsuna, Miyazaki, Hiromi, Hamada, Koji, Ono, Satoshi, Iwaya, Keiichi, Saitoh, Daizoh, Seki, Shuhji, Tanaka, Yuji
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Bacterial Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497398/
https://ncbi.nlm.nih.gov/pubmed/23027538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00787-12
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