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Fragment-Based Screening by Protein Crystallography: Successes and Pitfalls

Fragment-based drug discovery (FBDD) concerns the screening of low-molecular weight compounds against macromolecular targets of clinical relevance. These compounds act as starting points for the development of drugs. FBDD has evolved and grown in popularity over the past 15 years. In this paper, the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chilingaryan, Zorik, Yin, Zhou, Oakley, Aaron J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Molecular Diversity Preservation International (MDPI) 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497300/
https://ncbi.nlm.nih.gov/pubmed/23202926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131012857
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