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Fragment-Based Screening by Protein Crystallography: Successes and Pitfalls

Fragment-based drug discovery (FBDD) concerns the screening of low-molecular weight compounds against macromolecular targets of clinical relevance. These compounds act as starting points for the development of drugs. FBDD has evolved and grown in popularity over the past 15 years. In this paper, the...

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Bibliografski detalji
Glavni autori: Chilingaryan, Zorik, Yin, Zhou, Oakley, Aaron J.
Format: Artigo
Jezik:Inglês
Izdano: Molecular Diversity Preservation International (MDPI) 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497300/
https://ncbi.nlm.nih.gov/pubmed/23202926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131012857
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