Maintaining functional major histocompatibility complex diversity under inbreeding: the case of a selfing vertebrate

Major histocompatibility complex (MHC) genes encode proteins that present pathogen-derived antigens to T-cells, initiating the adaptive immune response in vertebrates. Although populations with low MHC diversity tend to be more susceptible to pathogens, some bottlenecked populations persist and even...

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Detalhes bibliográficos
Main Authors: Ellison, A., Allainguillaume, J., Girdwood, S., Pachebat, J., Peat, K. M., Wright, P., Consuegra, S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497237/
https://ncbi.nlm.nih.gov/pubmed/23075838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2012.1929
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