Maintaining functional major histocompatibility complex diversity under inbreeding: the case of a selfing vertebrate

Major histocompatibility complex (MHC) genes encode proteins that present pathogen-derived antigens to T-cells, initiating the adaptive immune response in vertebrates. Although populations with low MHC diversity tend to be more susceptible to pathogens, some bottlenecked populations persist and even...

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Main Authors: Ellison, A., Allainguillaume, J., Girdwood, S., Pachebat, J., Peat, K. M., Wright, P., Consuegra, S.
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2012
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497237/
https://ncbi.nlm.nih.gov/pubmed/23075838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2012.1929
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