Chitin Synthases with a Myosin Motor-Like Domain Control the Resistance of Aspergillus fumigatus to Echinocandins

Aspergillus fumigatus has two chitin synthases (CSMA and CSMB) with a myosin motor-like domain (MMD) arranged in a head-to-head configuration. To understand the function of these chitin synthases, single and double csm mutant strains were constructed and analyzed. Although there was a slight reducti...

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Detalhes bibliográficos
Main Authors: Jiménez-Ortigosa, Cristina, Aimanianda, Vishukumar, Muszkieta, Laetitia, Mouyna, Isabelle, Alsteens, David, Pire, Stéphane, Beau, Remi, Krappmann, Sven, Beauvais, Anne, Dufrêne, Yves F., Roncero, César, Latgé, Jean-Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497188/
https://ncbi.nlm.nih.gov/pubmed/22964252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00752-12
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