Chitin Synthases with a Myosin Motor-Like Domain Control the Resistance of Aspergillus fumigatus to Echinocandins

Aspergillus fumigatus has two chitin synthases (CSMA and CSMB) with a myosin motor-like domain (MMD) arranged in a head-to-head configuration. To understand the function of these chitin synthases, single and double csm mutant strains were constructed and analyzed. Although there was a slight reducti...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jiménez-Ortigosa, Cristina, Aimanianda, Vishukumar, Muszkieta, Laetitia, Mouyna, Isabelle, Alsteens, David, Pire, Stéphane, Beau, Remi, Krappmann, Sven, Beauvais, Anne, Dufrêne, Yves F., Roncero, César, Latgé, Jean-Paul
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Mechanisms of Resistance
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497188/
https://ncbi.nlm.nih.gov/pubmed/22964252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00752-12
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires