ω-Conotoxin GVIA Mimetics that Bind and Inhibit Neuronal Ca(v)2.2 Ion Channels

The neuronal voltage-gated N-type calcium channel (Ca(v)2.2) is a validated target for the treatment of neuropathic pain. A small library of anthranilamide-derived ω-Conotoxin GVIA mimetics bearing the diphenylmethylpiperazine moiety were prepared and tested using three experimental measures of calc...

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Detaylı Bibliyografya
Asıl Yazarlar: Tranberg, Charlotte Elisabet, Yang, Aijun, Vette, Irina, McArthur, Jeffrey R., Baell, Jonathan B., Lewis, Richard J., Tuck, Kellie L., Duggan, Peter J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497028/
https://ncbi.nlm.nih.gov/pubmed/23170089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md10102349
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