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Validation of a Novel Statistical Model for Assessing the Synergy of Combined-agent Cancer Chemoprevention

Lung cancer is the leading cause of cancer death, developing over prolonged periods through genetic and epigenetic changes induced and exacerbated by tobacco exposure. Many epigenetic changes including DNA methylation and histone methylation and acetylation are reversible, and agents that can modula...

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Autori principali: Fujimoto, Junya, Kong, Maiying, Lee, J. Jack, Hong, Waun Ki, Lotan, Reuben
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496745/
https://ncbi.nlm.nih.gov/pubmed/20663979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0129
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