Gene expression changes in human islets exposed to type 1 diabetic serum

A major obstacle to the success of islet cell transplantation as a standard treatment for labile type 1 diabetes mellitus is the immediate loss of up to 70% of the transplanted islet mass. Activation of the complement cascade and coagulation factors has been implicated in initiating the destruction...

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Bibliographic Details
Main Authors: Jackson, Andrew M., Kanak, Mazhar A., Grishman, Ellen K., Chaussabel, Damien, Levy, Marlon F., Naziruddin, Bashoo
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496656/
https://ncbi.nlm.nih.gov/pubmed/22885994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.21510
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