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Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages
Inflammatory neovascularization, such as choroidal neovascularization (CNV), occur in the presence of Notch expressing macrophages. DLL4s anti-angiogenic effect on endothelial cells (EC) has been widely recognized, but its influence on Notch signaling on macrophages and its overall effect in inflamm...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496480/ https://ncbi.nlm.nih.gov/pubmed/22869002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-012-9290-0 |
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