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Enhancing and limiting endothelin-1 signaling with a cell penetrating peptide mimicking the third intracellular loop of the ETB receptor

TAT (a 13-mer derived from the HIV-1 Tat protein) linked cell-permeable peptides deliver plasma membrane impermeable cargos into the cell. We investigated the effect of a TAT linked intracellular third loop (IC3) of the endothelin-1 (ET-1) type B receptor on ET-1 activation of ERK. The effect of thi...

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Detalhes bibliográficos
Main Authors: Sallum, Christine O., Wilson, Jamie L., Rupasinghe, Chamila, Berg, Eric, Yu, Jun, Green, Daniel S., Taylor, Linda, Mierke, Dale, Polgar, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496424/
https://ncbi.nlm.nih.gov/pubmed/22553998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2012.01405.x
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