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Targeting Receptor Tyrosine Kinases and Their Downstream Signaling with Cell-Penetrating Peptides in Human Pulmonary Artery Smooth Muscle and Endothelial Cells

Cell-penetrating peptide (CPP) intracellular delivery of receptor signaling motifs provides an opportunity to regulate specific receptor tyrosine kinase signal transductions. We targeted tyrosine residues Y740 and Y751 of the PDGF receptor β (PDGFRβ) and Y1175 of the VEGF receptor 2 (VEGFR2). The Y7...

詳細記述

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書誌詳細
出版年:Chem Biol Drug Des
主要な著者: Yu, Jun, Rupasinghe, Chamila, Wilson, Jamie L., Taylor, Linda, Rahimi, Nader, Mierke, Dale, Polgar, Peter
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390552/
https://ncbi.nlm.nih.gov/pubmed/25298192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12446
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