CCR2(+)CCR5(+) T Cells Produce Matrix Metalloproteinase-9 and Osteopontin in the Pathogenesis of Multiple Sclerosis

Multiple sclerosis (MS) is a demyelinating disease of the CNS that is presumably mediated by CD4(+) autoimmune T cells. Although both Th1 and Th17 cells have the potential to cause inflammatory CNS pathology in rodents, the identity of pathogenic T cells remains unclear in human MS. Given that each...

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Detalhes bibliográficos
Main Authors: Sato, Wakiro, Tomita, Atsuko, Ichikawa, Daijyu, Lin, Youwei, Kishida, Hitaru, Miyake, Sachiko, Ogawa, Masafumi, Okamoto, Tomoko, Murata, Miho, Kuroiwa, Yoshiyuki, Aranami, Toshimasa, Yamamura, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2012
Assuntos:
Clinical Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496198/
https://ncbi.nlm.nih.gov/pubmed/23071279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202026
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