Progranulin (GP88) tumor tissue expression is associated with increased risk of recurrence in breast cancer patients diagnosed with estrogen receptor positive invasive ductal carcinoma

INTRODUCTION: GP88 (progranulin) has been implicated in tumorigenesis and resistance to anti-estrogen therapies for estrogen receptor positive (ER(+)) breast cancer. Previous pathological studies showed that GP88 is expressed in invasive ductal carcinoma (IDC), but not in normal mammary epithelial t...

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Bibliographic Details
Main Authors: Serrero, Ginette, Hawkins, Douglas M, Yue, Binbin, Ioffe, Olga, Bejarano, Pablo, Phillips, Jeffrey T, Head, Jonathan F, Elliott, Robert L, Tkaczuk, Katherine R, Godwin, Andrew K, Weaver, JoEllen, Kim, Wes E
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496144/
https://ncbi.nlm.nih.gov/pubmed/22316048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3111
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