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Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticity
Smad proteins are the key intermediates of transforming growth factor-beta (TGF-β) signaling during development and in tissue homeostasis. Pertubations in TGF-β/Smad signaling have been implicated in cancer and other diseases. In the cell nucleus, Smad complexes trigger cell type- and context-specif...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496114/ https://ncbi.nlm.nih.gov/pubmed/22315972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3066 |
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